発表論文
2023年度
Masaki Horitani, Risa Yamada, Kanami Taroura, Akari Maeda, Toyoaki Anai, Satoshi Watanabe*
"Identification of Genes Responsible for the Synthesis of Glycitein Isoflavones in Soybean Seeds"
Plants, 13(2) (2024) 156
2022年度
Tatsuya Yamashita, Hiroki Matsuda, Kyohei Koizumi, Logu Thirumalaisamy, Myeongok Kim, Lumi Negishi, Hitoshi Kurumizaka, Yoriko Tominaga, Yoshihiro Takagi, Ken Takai, Taiga Okumura, Hidekazu Katayama, Masaki Horitani, Nazmul Ahsan, Yoshitaka Okada, Koji Nagata, Yohey Suzuki, Michio Suzuki*
"Heme Protein Identified from Scaly-Foot Gastropod can Synthesize Pyrite (FeS2) Nanoparticles."
Acta Biomater., 162 (2023) 110
Masato Ishizaka, Minghao Chen, Sun Narai, Yoshikazu Tanaka, Toyoyuki Ose, Masaki Horitani*, Min Yao*
"Quick and Spontaneous Transformation between [3Fe-4S] and [4Fe-4S] Iron-Sulfur Clusters in the tRNA-Thiolation Enzyme TtuA."
Int. J. Mol. Sci., 24 (2023) 833
Hanae Takeda, Kanji Shimba, Masaki Horitani, Tetsunari Kimura, Takashi Nomura, Minoru Kubo, Yoshitsugu Shiro*, Takehiko Tosha*
"Trapping of Mono-Nitrosyl Non-Heme Intermediate of Nitric Oxide Reductase by Cryo-photolysis of Caged Nitric Oxide."
J. Phys. Chem. B, 127 (2023) 846-854
上記論文はJPC誌のJPC誌の表紙を飾りました。
Kazuo Kobayashi*, Yuko Tsutsui Ito, Yuri Kasu, Masaki Horitani, Takahiro Kozawa
"Intramolecular Electron Transfer from Biopterin to FeII-O2 Complex in Nitric Oxide Synthases occurs at very Different Rates between Bacterial and Mammalian Enzymes：Direct Observation of a Catalytically Active Intermediate."
J. Inorg. Biochem., 238 (2023) 112035
堀谷 正樹、堀 洋
第5章 測定解析技術・第3節 "磁気共鳴EPRでヘムタンパク質の何をみるか？―活性中心の電子状態とミクロ分子環境―"
ヘムタンパク質の科学
監修:城 宜嗣、青野 重利、齋藤 正男
株式会社エヌ・ティー・エス (2022)
2021年度
Tomotaka Nagasawa, Masaki Horitani, Shin-ichi Kawaguchi, Shigeki Higashiyama, Yoichiro Hama, Susumu Mitsutake*
"The Molecular Mechanism of Phytosphingosine binding to FFAR4/GPR120 Differs from That of Other Fatty Acids."
FEBS Open Bio, 11 (2021) 3081-3089
Konan Ishida, Yuya Tsukamoto, Masaki Horitani*, Tomohisa Ogawa, Yoshikazu Tanaka*
"Biochemical Properties of CumA Multicopper Oxidase from Plant Pathogen, Pseudomonas Syringae."
Biosci. Biotechnol. Biochem. 85 (2021) 1995-2002
2020年度
堀谷 正樹
第7章 方法論・第6節 "金属タンパク質のESR"
生命金属ダイナミクス～生体内における金属の挙動と制御～
監修:城 宜嗣、津本 浩平、編集委員:古川 良明、神戸 大朋
株式会社エヌ・ティー・エス (2021)
Hanae Takeda, Tetsunari Kimura, Takashi Nomura, Masaki Horitani, Azusa Yokota, Akiko Matsubayashi, Shoko Ishii, Yoshitsugu Shiro, Minoru Kubo*, Takehiko Tosha*
"Timing of NO Binding and Protonation in the Catalytic Reaction of Bacterial Nitric Oxide Reductase as Established by Time-Resolved Spectroscopy."
Bull. Chem. Soc. Jpn. 93 (2020) 825-833
この論文は “Selected Paper”に選ばれました
2019年度
Minghao Chen, Masato Ishizaka, Shun Narai, Masaki Horitani, Naoki Shigi, Min Yao*, and Yoshikazu Tanaka*
"The [4Fe-4S] Cluster of Sulfurtransferase TtuA Desulfurizes TtuB during tRNA Modification in Thermus Thermophilus."
Comms. Biol. 3 (2020) 168
Masaki Horitani*, Kazuki Kusubayashi, Kyoka Oshima, Akane Yato, Hiroshi Sugimoto, and Keiichi Watanabe
"X-ray Crystallography and Electron Paramagnetic Resonance Spectroscopy Reveal Active Site Rearrangement of Cold-Adapted Inorganic Pyrophosphatase."
Sci. Rep. 10 (2020) 4368
Naoki Shigi*, Masaki Horitani, Kenjyo Miyauchi, Tsutomu Suzuki, and Misao Kuroki
"An Ancient Type of MnmA Protein is an Iron-Sulfur Cluster-Dependent Sulfurtransferase for tRNA Anticodons."
RNA, 25 (2020) 240-250
石坂 優人、陳 明皓、奈良井 峻、堀谷 正樹、田中 良和、姚 閔
"鉄硫黄クラスターが関与するtRNAチオ化修飾酵素の詳細な反応機構解明を目指した研究"
PF News, 37 (2019) 20-24
2017年度
Krista A. Shisler, Rachel U. Hutcheson, Masaki Horitani, Kaitlin S. Duschene, Adam V. Crain, Amanda S. Byer, Eric M. Shepard, Ashley Ramussen, Jian Yang, William E. Broderick, Jessica L. Vey, Catherine L. Drennan, Brian M. Hoffman, Joan B. Broderick*
"Monovalent Cation Activation of the Radical SAM Enzyme Pyruvate Formate-Lyase Activating Enzyme."
J. Am. Chem. Soc., 139 (2017) 11803-11813
Masaki Horitani, Katarzyna Grubel, Sean F. McWilliams, Bryan D. Stubbert, Brandon Q. Mercado, Ying Yu, Prabhuodeyara M. Gurubasavaraj, Nicholas S. Lees, Patrick L. Holland*, and Brian M. Hoffman*
"ENDOR Characterization of an Iron-Alkene Complex Provides Insight into a Corresponding Organometallic Intermediate of Nitrogenase."
Chem. Sci., 8 (2017) 5941-5948
Min Dong, Masaki Horitani, Boris Dzikovski, Jack H. Freed, Steven E. Ealick, Brian M. Hoffman*, and Hening Lin*
"Substrate-Dependent Cleavage Site Selection by Unconventional Radical SAM Enzymes in Diphthamide Biosynthesis."
J. Am. Chem. Soc., 139 (2017) 5680-5683
堀谷 正樹
"ラジカルSAM酵素における反応中間体捕捉と反応機構解析"
生物物理, 57, pp202-204 (2017)
堀谷 正樹
"先端磁気共鳴法による金属タンパク質研究"
電子スピンサイエンス, 15, pp20-26 (2017)
2016年度
Masaki Horitani#, Adam R. Offenbacher#, Cody A. Marcus Carr, Tao Yu, Veronika Hoeke, George E. Cutsail III, Sharon Hammes-Schiffer, Judith P. Klinman*, and Brian M. Hoffman*
"13C ENDOR Spectroscopy of Lipoxygenase-Substrate Complexes Reveals the Structural Basis for C-H Activation by Tunneling."
J. Am. Chem. Soc., 139 (2017) 1984-1997
#: These authors are equally contributed to this work.
Karamatullah Danyal, Sudipta Shaw, Taylor R. Page, Simon Duval, Masaki Horitani, Amy R. Marts, Dmitriy Lukoyanov, Dennis R. Dean, Simone Raugei, Brian M. Hoffman*, Lance C. Seefeldt*, and Edwin Antony*
"Negative Cooperativity in the Nitrogenase Fe Protein Electron Delivery Cycle."
Proc. Natl. Acad. Sci., 113 (2016) E5783-5791
Min Dong#, Masaki Horitani#, Boris Dzikovski, Maria-Eirini Pandelia, Carsten Krebs, Jack H. Freed, Brian M. Hoffman*, and Hening Lin*
"Organometallic complex formed by an unconventional radical S-adenosylmethionine enzyme."
J. Am. Chem. Soc., 138 (2016) 9755-9758
#: These authors are equally contributed to this work.
Masaki Horitani, Krista Shisler, William E. Broderick, Rachel U. Hutcheson, Kaitlin S. Duschene, Amy R. Marts, Brian M. Hoffman*, and Joan B. Broderick*
"Radical SAM catalysis via an organometallic intermediate with an Fe−[5'-C]-deoxyadenosyl bond."
Science, 352 (2016) 822-825
上記論文の紹介記事
Concentrates in Chemical & Engineering News 94, (2016) 11
PhysOrg.com, June 28 (2016) http://phys.org/news/2016-06-scientists-publish-vital-biochemical.html
2015年度
Mahesh Aitha, Abraham J. Moller, Indra D. Sahu, Masaki Horitani, David L. Tierney, and Micheal W. Crowder*
"Investigating the Position of the Hairpin Loop in New Delhi Mettalo-β-Lactamase, NDM-1, During Catalysis and Inhibitor Binding."
J. Inorg. Biochem., 156 (2016) 35-39
Masaki Horitani#, Amanda S. Byer#, Krista A. Shisler, Tilak Chandra, Joan B. Broderick*, and Brian M. Hoffman*
"Why Nature Uses Radical SAM Enzymes so Widely: Electron Nuclear Double Resonance Studies of Lysine 2,3-Aminomutase Show the 5’-dAdo• “Free Radical” is Never Free."
J. Am. Chem. Soc., 137 (2015) 7111-7121
#: These authors are equally contributed to this work.
上記論文はJACS誌のSpotlight（重要論文）に選ばれ、さらに表紙を飾りました。
Selected as “the cover of JACS”
Selected as “JACS Spotlight”
上記論文の紹介記事
Concentrates in Chemical & Engineering News 93, (2015) 29
それ以前の論文
Karen P. Chiang, Christopher C. Scarborough, Masaki Horitani, Nicholas S. Lees, Keying Ding, Thomas R. Dugan, William W. Brennessel, Eckhard Bill, Brian M. Hoffman, and Patrick L. Holland*
"Characterization of the Fe-H Bond in a Three-Coordinate Terminal Hydride Complex of Iron(I)."
Angew. Chem. Int. Ed., 51 (2012) 3658-3662
この論文は “Hot Paper”に選ばれました
Hiroshi Hori*, Haruhiko Yashiro, Kenta Ninomiya, Masaki Horitani, Takanori Kida, and Masayuki Hagiwara
"Low-Lying Electronic States of the Ferrous High-Spin (S = 2) Heme in Deoxy-Mb and Deoxy-Hb Studied by Highly-Sensitive Multi-Frequency EPR."
J. Inorg. Biochem., 105 (2011) 1596-1602
Sachiko Yanagisawa, Masaki Horitani, Hiroshi Sugimoto, Yoshitsugu Shiro, Norihiro Okada, and Takashi Ogura*
"Resonance Raman Study on the Oxygenate and the Ferryl-Oxo Species of Indoleamine 2,3-Dioxygenase During Catalytic Turnover."
Faraday Discuss., 148 (2010) 239-247
Takashi Ogura*, Sachiko Yanagisawa, Norihiro Okada, Masaki Horitani, Hiroshi Sugimoto, Yoshitsugu Shiro, and Evan H. Appleman
"Resonance Raman Identification Of A FeIV=O Type Reaction Intermediate During Indoleamine 2,3-Dioxygenase Reaction."
AIP Conf. Proc., 1267 (2010) 892-893
Sachiko Yanagisawa, Keiko Yotsuya, Yumi Hashiwaki, Masaki Horitani, Hiroshi Sugimoto, Yoshitsugu Shiro, Evan H. Appleman, and Takashi Ogura*
"Identification of the Fe-O2 and the Fe=O Heme Species for Indoleamine 2,3-Dioxygenase during Catalytic Turnover."
Chem. Lett., 39 (2010) 36-37
この論文はEditor’s choice articleに選ばれました
Masaki Horitani, Haruhiko Yashiro, Masayuki Hagiwara, and Hiroshi Hori*
"Multi-Frequency and High-Field EPR Study of Manganese (III) protoporphyrin IX reconstituted Myoglobin with an S = 2 Integer Electron Spin."
J. Inorg. Biochem., 102 (2008) 781-788
Haruhiko Yashiro, Takanari Kashiwagi, Masaki Horitani, Fumio Hobo, Hiroshi Hori, and Masayuki Hagiwara*
"Development of a Multi-Frequency ESR system with High Sensitivity."
J. Phys.: Conf. Sers., 51 (2006) 576-579
堀谷 正樹
"海外だより～海外留学のすゝめ～""
生物物理, 53, pp227-228 (2013)
堀谷 正樹
"多周波数・強磁場EPR(MFEPR)法を用いた整数スピン系金属タンパク質研究の新たな展開
～ Mn3+ポルフィリン置換ミオグロビン(S = 2) ～"
平成１９年度大阪大学低温センター研究報告書、大阪大学、pp.73-76 (2007)
堀谷 正樹
"S = 2スピン系ヘムタンパク質の電子常磁性共鳴（EPR）による解析
― Mn3+置換ミオグロビンの場合 ―"
平成１５年度大阪大学低温センター研究報告書、大阪大学、pp.35-38 (2003)